This is a list of published trials which used Red Pill or our comprehensive randomisation service. Hundreds more trials have also been set-up on our popular simple randomisation service.
The clinical impact of customised Positive Airway Pressure (PAP) therapy interfaces vs usual care in the treatment of patients with sleep disordered breathing
A randomised controlled trial to investigate the effect of structured education on people at high risk of cardiovascular disease" where name like '3R (Ready to Reduce Risk) study
A prospective randomised controlled study of a directed psycho-educational tool to prevent psychological sequelae following Paediatric Intensive Care admission
Evaluating the clinical and cost-effectiveness of permissive hypotension in critically ill patients aged 65 years or over with vasodilatory hypotension
Acetic Acid guided biopsies in Barrett’s surveillance for neoplasia detection versus non-targeted biopsies (Seattle protocol): A feasibility study for a randomised tandem endoscopy trial. The ABBA study
The use of Benralizumab, an interleukin-5 receptor-α monoclonal antibody as treatment of acute exacerbations of airways disease
Acetabular Fractures in older patients Intervention Trial. A feasibility study comparing three methods of treatment of acetabular fractures in older patients; surgical fixation versus surgical fixation and hip replacement versus non-surgical treatment
Acupuncture treatment with threatened miscarriage: an exploratory study. Trial being conducted by the Centre for Complementary Medicine Research, University of Western Sydney.
Antidepressants Trial in Parkinson's Disease (ADepT-PD)
Aggression Following Traumatic Brain Injury (TBI): Effectiveness of Risperidone – a Feasibility RCT
A prospective, randomised, placebo-controlled double blind, multi-centre study of the effects of Irbesartan on aortic dilatation in Marfan syndrome.
Auto-inflation in children with otitis media with effusion (AIRS). A multi-centre trial being run by the Primary Care Clinical Trials Unit at the University of Oxford.
ANTidepressants to prevent reLapse in dEpRession
Evaluating the benefit of Additional Platelet inhibition in Acute Coronary Syndrome patients with high platelet reactivity undergoing PCI. A Randomised comparison of prasugrel versus clopidogrel re-loading in patients with ACS undergoing urgent PCI with persistent high platelet reactivity.
A randomised phase II study to seek evidence that the addition of a potent src-inhibitor, AZD0530, to conventional aromatase inhibition, delays the onset of endocrine resistance in post- menopausal women with advanced breast cancer.
Combined multi-marker screening and randomised patient treatment with aspirin for evidence-based pre-eclampsia prevention.
Albumin To prevenT Infection in chronic liveR failurE
Azathioprine Immunosuppression and Disease Modification in Parkinson’s Disease (AZA-PD): a randomised double-blind placebo-controlled phase II trial
Use of Endothelin-1 antagonists in patients with established pulmonary hypertension and fibrotic lung disease - a randomised, placebo controlled, double-blinded study.
Phase 2a two-site randomised controlled trial to determine safety of and adherence with a new ‘Binocularly Balanced Viewing’ treatment for unilateral amblyopia compared with standard treatment in children age 3-8 years
A double-blinded, randomised, placebo-controlled trial of liraglutide 3.0 mg in patients with poor weight-loss and a suboptimal glucagon-like peptide-1 response following bariatric surgery.
A double-blinded, randomised, placebo- controlled trial of semaglutide 2.4 mg in patients with poor weight-loss following bariatric surgery
A randomized, controlled trial of the use of a dedicated ballooned intercostal drain
Balanced Salt Solution Versus 0.9% Saline Infusion for Prevention of Contrast-induced Acute Kidney Injury
Ballon-pump Coronary Intervention Study.
Safety and efficacy of Belimumab After B cell depleTion therapy in systemic LUPUS erythematosus
Beyond Allergic Th2 Severe Asthma (BEAT-SA)
British Heart Foundation Randomised Trial of Routine Cerebral Embolic Protection in Transcatheter Aortic Valve Implantation
Pilot cluster randomised trial of an evidence based intervention to reduce avoidable hospital admissions in residents in care homes (the Better Health in Residents in Care Homes study)
Efficacy of BIC/F/TAF versus standard of care in the treatment of new HIV infection diagnoses in the context of ‘test and treat’
A feasibility investigating different interventions for the treatment of benign paroxysmal positional vertigo in acute traumatic brain injury patients
BRAVE Trial. Broad-spectrum Cognitive Remediation Available to Veterans: Effects of a Brain Plasticity-based Program in Mild Traumatic Brain Injury (mTBI). Posit Science.
Morphine for the relief of breathlessness in heart failure.
BRIDE (Barrett's Randomised Intervention for Dysplasia by Endoscopy) - a feasibility study
Randomised double-blind controlled trial of connectivity guided theta burst transcranial magnetic stimulation versus repetitive transcranial magnetic stimulation for treatment resistant moderate to severe depression: evaluation of efficacy, cost effectiveness and mechanism of action
BT-LIFE, Brain Tumours, Lifestyle Interventions and Fatigue
Gastric BYpass or adjustable gastric BANDing surgery or Sleeve Gastrectomy surgery to treat morbid obesity: a multi-centre randomised controlled trial.
A phase III, open, randomised, multi-site trial to assess the clinical and cost-effectiveness of early parenteral, compared with early enteral, nutritional support in critically ill patients.
Cambridge Brain Mets Trial 1
A Randomised Controlled Trial for People with Established Type 2 Diabetes during Ramadan: Canagliflozin (Invokana™) vs. standard dual therapy regimen.
The feasibility of recruiting and undertaking a randomised controlled trial to help with coping using two talking interventions, ACT or a Talking Control for people receiving treatment to control their cancer symptoms.
A phase IIa/b, randomised, double-blind, placebo-controlled, single-site, parallel group clinical trial to examine cannabidiol (CBD) as a pharmacological treatment for cannabis dependence in a young cannabis dependent population.
CanTalk: the clinical and cost effectiveness of CBT plus treatment as usual for the treatment of depression in advanced cancer; a randomised controlled trial.
Efficacy, safety and impact on antimicrobial resistance of duration and dose of amoxicillin treatment for young children with Community-Acquired Pneumonia (CAP): A randomised controlled trial
The Coronary Artery Revascularisation in Diabetes (CARDia) trial
Efficacy and safety of novel treatment options for adults with COVID-19 pneumonia. A double-blinded, randomized, multi-stage, 6-armed placebo-controlled trial in the framework of an adaptive trial platform
CCMR Two: A phase IIa, randomised, double-blind, placebo-controlled trial of the ability of the combination of metformin and clemastine to promote remyelination in people with relapsing- remitting multiple sclerosis already on disease-modifying therapy
Low-dose atropine eye drops to reduce progression of myopia in children: a multi- centre placebo controlled randomised trial in the United Kingdom, (CHAMP UK)
Congestive Heart failure Cardiopoietic Regenerative Therapy (CHART-1) trial. Efficacy and Safety of Bone Marrow-Derived Mesenchymal Cardiopoietic Cells (C3BS-CQR-1) for the treatment of chronic advanced ischemic Heart Failure. Cardio3 BioSciences SA.
Cholinesterase inhibitors to prevent falls in Parkinson’s Disease: A multicentre, phase III, double blind, randomised control trial of the cholinesterase inhibitor, rivastigmine versus placebo to prevent falls in Parkinson’s disease
A 2x2 factorial randomised examiner blind open label trial to determine the clinical and cost-effectiveness of hypertonic saline (HTS 6%) and carbocisteine for airway clearance versus usual care over 52 weeks in bronchiectasis
A randomised, double blind, controlled mechanistic study of rituximab and belimumab combination therapy in PR3 ANCA-associated vasculitis
Conventional versus Minimally Invasive extra-corporeal circulation in patients undergoing Cardiac Surgery: a randomised controlled trial
Cognitive behavioural therapy or medication for psychosis - a randomised evaluation.
A randomised phase II pilot study of 3 weekly Cabazitaxel versus weekly Paclitaxel chemotherapy in the first line treatment of HER2 negative breast cancer.
Control, Fludrocortisone or Midodrine for the treatment of Orthostatic Hypotension: A Randomised Controlled Trial
Increasing uptake and adherence to long-acting reversible contraceptive (LARC) methods in young women
The effect of canagliflozin 300mg in subjects without diabetes after bariatric surgery on glucose homeostatis (the CONTROL study). A proof of concept, randomised, open label, two period cross over study
COlchicine for preventioN of Vascular Inflammation in Non-CardioEmbolic stroke – a randomised clinical trial of low-dose colchicine for secondary prevention after stroke
A Multicenter, Prospective, Randomized Controlled Trial to Assess Cooling as an Adjunctive Therapy to Percutaneous Intervention in Patients with Acute Myocardial Infarction
A Randomised Controlled Trial of Mepolizumab Initiated During Admission to Hospital for a Severe Exacerbation of Eosinophilic COPD
A randomised placebo-controlled trial of anti-ST2 in COPD (COPDST₂OP)
CORE Phase 3. A randomised controlled trial of a peer-provided self-management intervention for people leaving CRT care.
A randomised phase II study evaluating cediranib vs. cediranib and saracatanib in patients with relapsed metastatic clear cell renal cancer.
A Randomised Controlled Trial of plasma exchange with standard of care compared to standard of care alone in the treatment of severe COVID- 19 infection
Tranexamic acid for the treatment of significant traumatic brain injury: an international randomised, double blind placebo controlled trial
Microbleeds and genetic risk factors to predict the risk of intracranial haemorrhage in patients treated with anticoagulation following cardioembolic stroke due to atrial fibrillation.
Complete Versus Lesion-only PRimary PCI PiloT Study. Prospective observational registry and open multi-centre randomised controlled trial (RCT) in a subset of patients with multi-vessel coronary artery disease.
A Phase I, Storer Design, open-label, cross-sectional, single site trial of ANX776 in healthy volunteers, progressive glaucoma/glaucoma-suspect/ocular hypertensive subjects and non-arteritic anterior ischaemic optic neuropathy subjects.
A phase II, open label, non-randomised, single centre, clinical trial of ANX776 in healthy volunteers and patients with Glaucoma, Age-Related Macular Degeneration and Optic Neuritis
Dapagliflozin, Exercise Training and physicAL function: the DETA trial
An Investigation to Evaluate an Over-The-Wire FFR Infusion Microcatheter (HYPEREM™IC) for Measuring Fractional Flow Reserve (FFR)
A pragmatic, multicentre, placebo-controlled, 3-arm, double-blinded, randomised controlled trial, incorporating an internal pilot, to determine the role of bronchodilators in preventing exacerbations of bronchiectasis
The DHA (docosahexaenoic acid) Oxford Learning and Behaviour (DOLAB II) Study. Does taking an Omega 3 food supplement help children’s learning and behaviour?
Randomised controlled trial of nasal decongestants versus placebo to prolong treatment free periods from continuous positive airway pressure therapy in mild to moderate obstructive sleep apnoea
Early switch to oral antibiotic therapy in patients with low risk neutropenic sepsis.
A feasibility study of a psychological intervention to address alcohol misuse for people with mild to moderate learning disabilities living in the community
A Randomised Placebo Controlled Trial of the effectiveness of Early MEtformin in Addition to Usual Care in the Reduction of Gestational Diabetes Mellitus Effects
An Investigation into the efficacy of Mirococept (APT070) for preventing ischaemia-reperfusion injury in the kidney allograft (EMPIRIKAL). King's College London and Guy's & St Thomas' NHS Foundation Trust.
The effect of remote ischaemic preconditioning and glyceryl trinitrate on peri-operative myocardial injury in cardiac bypass surgery patients (ERIC-GTN study) - a four arm randomised, controlled trial.
Effect of Remote Ischaemic Conditioning on clinical outcomes in ST-segment elevation myocardial infarction patients undergoing Primary Percutaneous Coronary Intervention (ERIC-PPCI): A multicentre randomised controlled clinical trial
Effect of Remote Ischaemic preConditioning on clinical outcomes in patients undergoing Coronary Artery Bypass Graft surgery. A multicentre randomised controlled clinical trial to determine whether remote ischaemic preconditioning (RIC) improves clinical outcomes after cardiac surgery.
A randomised, double blind, placebo controlled, single centre, 60 week, trial of Exenatide for the treatment of moderate severity Parkinson's disease.
A Phase IIa, open label, single-site, 48 week randomised controlled trial evaluating the safety and efficacy of Exenatide once-weekly in the treatment of patients with Multiple System Atrophy
A randomised, double blind, parallel group, placebo controlled, Phase 3 trial of Exenatide once weekly over 2 years as a potential disease modifying treatment for Parkinson's disease.
FIRST-line support for Assistance in Breathing in Children (FIRST-ABC): A master protocol of two randomised trials to evaluate the non-inferiority of high flow nasal cannula (HFNC) versus continuous positive airway pressure (CPAP) for non-invasive respiratory support in paediatric critical care
Randomised Feasibility Study of a Physiotherapy Programme for Patients with Functional Motor Symptoms (FMS).
A phase IIa, randomized, 2-arm parallel-group, placebo-controlled, double-blind, multi-centre trial to evaluate safety, tolerability, anti-inflammatory and cardio- protective effects after intravenous and oral administration of KAND567 in ST-elevation myocardial infarction (STEMI) patients undergoing percutaneous coronary intervention
Finding the optimal cooling tempeRature after Out-of-hoSpiTal cardiac arrest. Zoll Circulation Inc.
Randomised controlled trial of plasma cell depletion for severe Graves’ disease
Two-armed, double blind, randomised, controlled trial with ursodeoxycholic acid (UDCA) versus placebo for the treatment of Gestational Diabetes Mellitus (GDM)
Tranexamic acid for the treatment of gastrointestinal haemorrhage: an international randomised, double blind placebo controlled trial
Hughes Abdominal Repair Trial
HEAL trial - Hepatic Encephalopathy And LOLA. Efficacy of intravenous 'L-ornithine L-aspartate' in reversal of overt acute hepatic encephalopathy in patients with liver cirrhosis: a prospective, randomized, double-blind, placebo controlled trial.
Hypothermia for Encephalopathy in Low and Middle-Income Countries (HELIX) trial
Randomised controlled trial of a web-based self management programme (HeLP-Diabetes) for people with type 2 diabetes in primary care.
A randomised double-blind, placebo-controlled phase I/IIa trial to investigate the effect of depletion of serum amyloid P component (SAP) on the immune response to DNA vaccination in healthy male volunteers.
HalOPeridol Effectiveness trial. A randomised, double-blind, placebo-controlled trial to compare the early administration of intravenous haloperidol versus placebo in the prevention and treatment of delirium in critically ill ventilated patients.
Randomised controlled trial of hospital at home directed by the DECAF score versus standard inpatient care for patients admitted with an acute exacerbation of COPD and embedded health economic and qualitative studies.
A phase II randomised placebo controlled double blinded trial of Interleukin 1 blockade in Acute Severe Colitis
Iron and Chronic Obstructive Pulmonary Disease COPD Exercise Trial. To test the hypothesis that intravenous iron improves exercise performance in COPD as measured by constant rate cycle ergometry.
Improving Mood with Psychoanalytic And Cognitive Therapies. Trial of Specialist Clinical Care (SCC) vs. Cognitive Behavioural Therapy (CBT) vs. Short Term Psychoanalytical Psychotherapy (STTP).
The Immediate Management of the Patient with Ruptured Aneurysm: Open Versus Endovascular repair. Imperial College, London.
INTERIM: a randomised phase II feasibility study of INTERmittent versus continuous dosing of oral targeted combination therapy In patients with BRAFV600 mutant stage 3 unresectable or metastatic Melanoma
Effects of intravenous iron in COPD
The efficacy of Indwelling Pleural Catheter placement versus IPC placement PLUS sclerosant (talc) in patients with malignant pleural effusions managed exclusively as out-patients.
Low-dose interleukin-2 for the reduction of vascular inflammation in Acute Coronary Syndromes
Investigating the effect of post-operative home jejunostomy tube feeding on quality of life and nutritional parameters in patients with oesophago-gastric cancer: A pilot study
Clinical trial examining the effect of ketamine in combination with CBT on relapse rate in alcoholics.
Ketogenic diet in infants with epilepsy (KIWE)
Randomized Controlled Trial to evaluate the effectiveness of an intervention using mobile technology for the treatment of depressive symptoms in people with diabetes and/or hypertension
The aim of this study is to determine the efficacy of a novel therapy in the treatment for anorexia nervosa (AN), namely the Loughborough Eating disorders Activity theraPy (LEAP). LEAP is an innovative therapy that addresses the role of extreme exercise in the maintenance of AN using cognitive techniques and behavioural experiments and is fully integrated with an established manualised cognitive behavioural therapy for AN (mCBT-AN).
Health-Related Quality of Life in two treatment pathways for primary open angle glaucoma and ocular hypertension: a randomised controlled trial of initial selective laser trabeculoplasty versus conventional medical therapy.
Impact of Liraglutide on cardiac function and structure in young adults with type 2 diabetes: an open-label, randomised active-comparator trial.
A Multicenter Randomized Controlled Trial of Therapeutic Hypothermia plus Magnesium Sulphate (MgSO4) vs. Therapeutic Hypothermia plus Placebo in the management of Term babies with Hypoxic Ischemic Encephalopathy. Hamad Medical Corporation.
Treating neovascular age-related Macular degeneration with Aflibercept: a pilot 24 month, multi-centre randomised controlled trial comparing Standard Care with an individualised Treat and Extend regimen.
Multi-arm trial of Inflammatory Signal Inhibitors for COVID-19
Phase II, dose ranging, efficacy study of anti-thymocyte globulin (ATG) within 6 weeks of diagnosis of type 1 diabetes (T1D)
A phase III, randomised, double blinded, headto-head, single-site, cross-over trial of lamotrigine versus mexiletine for nondystrophic myotonias (MEND)
Methylphenidate versus placebo for fatigue in advanced cancer
Metformin to prevent progression of sarcopenia and frailty in older people – a double blind, randomised controlled proof of concept trial
MINeralocorticoid receptor antagonist pretreatment to MINIMISE reperfusion injury after ST-Elevation Myocardial Infarction (STEMI).
Maraviroc in HIV Post Exposure Prophylaxis (MiPEP) Trial. Randomised controlled trial of the tolerability and completion of maraviroc compared to Kaletra in combination with Truvada for HIV post-exposure prophylaxis.
A proof of concept clinical trial investigating the effects of IL-1ra upon markers of inflammation in patients with Non-ST elevation myocardial infarction.
SIMVASTATIN IN SECONDARY PROGRESSIVE MULTIPLE SCLEROSIS - A double-blind, randomised, placebo-controlled multi-site study of high dose simvastatin treatment for secondary progressive multiple sclerosis: impact on vascular perfusion and oxidative damage
A phase 3 randomised, double blind, clinical trial investigating the effectiveness of repurposed simvastatin compared to placebo, in secondary progressive multiple sclerosis, in slowing the progression of disability
Randomized Controlled Trial Comparing Intracoronary Administration of Adenosine or Sodium Nitroprusside to Control for Attenuation of Microvascular Obstruction During Primary Percutaneous Coronary Intervention.
The TB Reach MXU Peer Study. A cluster randomised controlled trial evaluating the impact of peer educators on uptake of MXU screening for TB among homeless populations.
Amino acid regimen and intravenous lipid composition in preterm parenteral nutrition: a randomised controlled trial of Nutritional Evaluation and Optimisation in Neonates.
A phase II double-blind, randomised, placebo controlled trial of neuroprotection with phenytoin in acute optic neuritis. Sponsored by UCL and funded by the National Multiple Sclerosis Society and the Multiple Sclerosis Society of Great Britain and Northern Ireland.
A single blinded, multi-centre site, feasibility study to evaluate the ability to randomise men with prostate cancer into a trial comparing NeuroSAFE Robotic assisted radical prostatectomy (RALP) to standard Robotic assisted radical prostatectomy (RALP)
A randomised, phase II, double blind, controlled mechanistic study of obinutuzumab versus rituximab in ANCA-associated vasculitis
OPtimal TIMing of Anticoagulation after acute ischaemic Stroke: a randomised controlled trial
Therapist-guided, parent-assisted remote digital behavioural intervention for tics in children and adolescents with Tourette syndrome: an internal pilot study and single-blind randomised controlled trial
PAciFy Cough: A multicentre, double blind, placebo controlled, crossover trial of morphine sulfate for the treatment of PulmonAry Fibrosis Cough
What are the indications for Prescribing ANtiDepressAnts that will lead to a clinical benefit? A Phase IV, double-blind randomised placebo-controlled, parallel group multi-site trial; of sertraline compared to placebo in patients presenting with depressive symptoms in primary care where treatment with SSRIs is uncertain.
Effectiveness of a Mentalization-based therapeutic intervention for parents in conflict over their children: a randomised controlled trial. Coordinated by The Tavistock Centre for Couple Relationships (TCCR).
Partner: Platinum & Parp-Inhibitor for neo-adjuvant treatment of Triple Negative and/or BRCA Positive Breast Cancer
Evaluation of Positive Behaviour Support (PBS). Randomised controlled trial to evaluate the clinical and cost effectiveness of PBS following standardised training of staff in routine clinical practice in community intellectual disability services.
Randomised Phase II clinical trial PIONEER- A Pre-operative wIndOw study of Letrozole plus PR agonist (Megestrol Acetate) versus Letrozole aloNE in post-menopausal patients with ER-positive breast cancer
PlasmaLyte Usage and kidney Transplant Outcomes in children
POWAR Study (Prophylaxis Of Wound infections - Antibiotics in Renal donation). Are prophylactic antibiotics necessary before laparoscopic living kidney donation? A double blind, randomised, controlled trial.
A randomised double-blind controlled phase III study to compare the efficacy and safety of intravenous ferric carboxymaltose with placebo in patients with anaemia undergoing major open abdominal surgery.
Pulmonary protection with low frequency ventilation during cardiopulmonary bypass: a prospective randomised study.
Platelet Responsiveness and Outcome from Platelet Transfusion. Does inherent variation in donor platelet function affect the clinical efficacy of apheresis platelets? A randomised double blind single centre trial.
A multi-centre, randomised controlled trial of the clinical and cost-effectiveness of early, goal-directed, protocolised resuscitation for emerging septic shock.
A Randomised trial of Pulmonary Metastasectomy in Colorectal Cancer. This is a two-stage randomised feasibility study. Patients will be firstly registered for evaluation and if subsequently eligible, randomised to active monitoring versus active monitoring with pulmonary metastasectomy.
Reducing pathology in Alzheimer's Disease through Angiotensin taRgeting. University of Bristol School of Social & Community Medicine
Rivaroxaban in Antiphospholipid Syndrome (RAPS) Trial (EudraCT 2012-002345-38).
Pilot study for a randomised controlled trial of home based reach to grasp training for people after stroke.
A randomised controlled trial of red cell washing for the attenuation of transfusion associated organ injury in cardiac surgery.
Randomised, double-blind, placebo controlled multi-centre study to assess the efficacy, tolerability and safety of Enterosgel® in the treatment of Irritable Bowel Syndrome with Diarrhoea (IBS-D) in adults (RELIEVE IBS-D)
Randomised double blind placebo-controlled trial to determine if remote ischaemic preconditioning (RIPC) improves renal function after transplantation.
Revascularisation for Ischaemic Ventricular Dysfunction - a multicentre prospective randomised open controlled trial. The aim is to evaluate the efficacy and safety of percutaneous coronary intervention compared to optimal medical therapy alone for ischaemic left ventricular dysfunction.
A double blind randomised controlled trial to determine whether IV administered Kineret® inhibits the central nervous system (CNS) inflammatory response in patients with SAH
A novel diagnostic screening procedure for antipsychotic-induced movement disorders.
Smoking Cessation for Severe Mental Ill Health Trial
A feasibility study to inform the development of a multicentre randomised controlled trial of an asthma-tailored pulmonary rehabilitation programme versus usual care for individuals with severe asthma.
Can simvastatin significantly reduce the amount of immunosuppressive medication required by patients with sight threatening uveitis? A phase IIb, single site, randomized, placebo controlled, double blinded trial. A UCL trial funded by the Moulton Trust.
Surgical and large bore pleural procedures in Malignant Pleural Mesothelioma And Radiotherapy Trial. A multi-centre trial being conducted by the Oxford Respiratory Trials Unit (University of Oxford).
Diabetes Prevention using SMS trial. A mobile phone intervention for lifestyle change in people with impaired glucose regulation (high risk at developing type 2 diabetes). Imperial College London.
SNAP (Silicon Nitride and PEEK) Trial. A Clinical Study of the Amedica Corporation Interbody Fusion Devices for PLIF. The primary objective is to compare the average improvement in Roland Morris Disability Questionnaire for Valeo OL patients versus those that receive similarly-shaped PEEK cages.
Sedentary behaviour in older adults: investigating a new therapeutic paradigm. Work Package 3: Investigating the effect of sedentary time, reduced sedentary time and increased light-intensity physical activity on metabolic and psychological health in older adults. University of Leicester.
Study of two regimens of TicagrElor compared to clopidogrel in patients undergoing ELective Percutaneous Coronary Intervention (STEEL PCI). Sheffield Teaching Hospitals NHS Foundation Trust.
A multicentre double-blind placebo-controlled randomised trial of SerTRaline for AnxieTy in adults with a diagnosis of Autism
A randomised controlled Trial of high and low dose Avastin® for Neovascular macular Degeneration in the East Midlands.
Evaluating the efficacy of thoracoscopy and talc poudrage versus pleurodesis using talc slurry. A multi-centre trial being conducted by the Oxford Respiratory Trials Unit (University of Oxford).
Total Ankle Replacement Versus Arthrodesis Trial: A randomised, multi-centre, non-blinded, prospective, parallel group trial of total ankle replacement (TAR) versus ankle arthrodesis, comparing clinical outcomes and cost-effectiveness.
Investigating Aspirin and Ticagrelor for the prevention of Tumour cell-induced platelet aggregation
Pharmacokinetics of intramuscular tranexamic acid in trauma patients: a clinical trial (Acronym: Trauma-INTACT)
The Evaluation of blood pressure treatment stratified according to Central Aortic Systolic Pressure (CASP) in Young Hypertensive Patients
A randomised controlled pilot trial of the feasibility and safety of therapy withdrawal in asymptomatic patients with a prior diagnosis of dilated cardiomyopathy and recovered cardiac function
A randomised controlled trial of Polyglactin 910 Triclosan coated sutures versus standard Polyglactin 910 sutures in patients aged 18 or over undergoing primary unilateral hip and knee arthroplasty in the Department of Trauma and Orthopaedics at University College London Hospital
A Phase 2b randomised, double blind, placebo-controlled trial of trimetazidine therapy in patients with non-obstructive hypertrophic cardiomyopathy (HCM). The sponsor is University College London (UCL).
Can text messages increase safer sexual health behaviours in young people? Pilot Trial
Phase II Multi-centre, double-blind, randomized trial of Ustekinumab in adolescents with new-onset type 1 diabetes
Preoperative Volume Replacement vs. usual care in Diabetic patients having CABG surgery, a randomised controlled Trial.
Tranexamic Acid for the Treatment of Postpartum Haemorrhage: an international Randomised, Double Blind, Placebo Controlled Trial.
A multicenter randomized controlled trial testing the app 'Young with Diabetes'
A double blind randomised controlled trial examining the effect of intravenous zoledronic acid on pleural tumour progression, pleural fluid production, breathlessness and quality of life in patients with malignant pleural disease.
A prognostic model that may be used as an aid to estimate the risk of incident locomotor disability within 7 years. Developed from data collected in the British Women's Heart and Health Study.
Prognostic model for predicting outcome after traumatic brain injury
A prognostic model that may be used as an aid to estimate the risk of coronary and cardiovascular death in patients with suspected angina.